Hs04815117_cn

• Gene Symbol: PPA2
• Assay Reference Genome Location: Chr.4:105389677 on build GRCh38
• Cytoband: 4q24

Target Gene Details

• Entrez Gene ID: 27068
• Gene Name: pyrophosphatase (inorganic) 2
• Gene Aliases: HSPC124, SID6-306
• Location: Chr.4:105369077-105474070 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPA2	NM_006903.4			NP_008834.3
	NM_176866.2			NP_789842.2
	NM_176867.3			NP_789843.2
	NM_176869.2			NP_789845.1
	AB026722.1			BAA84701.1
	AF161473.1			AAF29088.1
	AF217187.1			AAG36781.1
	AK000466.1			BAA91184.1
	AK289607.1
	AL136655.1			CAB66590.2
	BC022803.1			AAH22803.1
	BC039462.1			AAH39462.2
	BC057219.1			AAH57219.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1000196	Chr.4:103475625 - 106148054 on Build GRCh38	Loss	CXXC4 PPA2 LOC101929468 ARHGEF38-IT1 TET2 LOC101929529 TBCK INTS12 TET2-AS1 NPNT ARHGEF38 LOC101929577 GSTCD TACR3
nsv830027	Chr.4:105300853 - 105485581 on Build GRCh38	Gain	PPA2 TET2-AS1
nsv595007	Chr.4:104948391 - 105445052 on Build GRCh38	Loss	PPA2 TET2 TET2-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

pyrophosphatase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
protein dephosphorylation
diphosphate metabolic process

Function(s)

magnesium ion binding
inorganic diphosphatase activity
protein serine/threonine phosphatase activity