Hs04820415_cn

• Gene Symbol: MXD4
• Assay Reference Genome Location: Chr.4:2258589 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 10608
• Gene Name: MAX dimerization protein 4
• Gene Aliases: MAD4, MST149, MSTP149, bHLHc12
• Location: Chr.4:2247432-2262143 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MXD4	NM_006454.2			NP_006445.1
	XM_011513388.2			XP_011511690.1
	XM_017007655.1			XP_016863144.1
	XM_017007656.1			XP_016863145.1
	AF040963.1			AAB97009.1
	AF082740.1			AAF98553.1
	AF187724.1			AAQ13695.1
	BC002713.2			AAH02713.1
	BC068060.1			AAH68060.1
	BT019969.1			AAV38772.1
	BT019970.1			AAV38773.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508990	Chr.4:2246239 - 2324327 on Build GRCh38	Insertion	MIR4800 MXD4 ZFYVE28
nsv593377	Chr.4:2246106 - 2261919 on Build GRCh38	Loss	MIR4800 MXD4
nsv4200	Chr.4:2252081 - 2286377 on Build GRCh38	Insertion	MXD4 ZFYVE28
nsv1009347	Chr.4:2200935 - 2516063 on Build GRCh38	Gain	MIR4800 POLN MXD4 ZFYVE28 HAUS3 RNF4 CFAP99
dgv8912n54	Chr.4:2257123 - 2262637 on Build GRCh38	Loss	MXD4
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	SH3BP2 MXD4 ZFYVE28 FAM193A ADD1 MFSD10 MIR4800 POLN C4orf48 NOP14-AS1 NOP14 HAUS3 NAT8L RNF4 TNIP2 CFAP99
nsv593388	Chr.4:2257730 - 2266399 on Build GRCh38	Gain	MXD4
nsv527189	Chr.4:2243138 - 2276689 on Build GRCh38	Loss	MIR4800 MXD4 ZFYVE28
dgv8911n54	Chr.4:2253738 - 2262338 on Build GRCh38	Loss	MXD4
dgv8910n54	Chr.4:2249015 - 2262496 on Build GRCh38	Loss	MIR4800 MXD4
nsv829838	Chr.4:2155167 - 2349950 on Build GRCh38	Loss	MIR4800 POLN MXD4 ZFYVE28 HAUS3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of cell proliferation

Function(s)

DNA binding
transcription corepressor activity
protein binding
protein dimerization activity