Hs04929961_cn

• Gene Symbol: STK17A
• Assay Reference Genome Location: Chr.7:43588493 on build GRCh38
• Cytoband: 7p13

Target Gene Details

• Entrez Gene ID: 9263
• Gene Name: serine/threonine kinase 17a
• Gene Aliases: DRAK1
• Location: Chr.7:43583093-43627379 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
STK17A	NM_004760.2			NP_004751.2
	XM_017012792.1			XP_016868281.1
	AB011420.1			BAA34126.1
	BC023508.2			AAH23508.2
	BC047696.1			AAH47696.1
	BI461892.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3612997	Chr.7:43585283 - 43592494 on Build GRCh38	Loss	STK17A
nsv606736	Chr.7:43587460 - 43591529 on Build GRCh38	Loss	STK17A
nsv606717	Chr.7:43564508 - 43592243 on Build GRCh38	Loss	STK17A HECW1
esv3612993	Chr.7:43438543 - 43609526 on Build GRCh38	Gain	COA1 STK17A LOC100506895 HECW1
dgv11295n54	Chr.7:43585908 - 43595683 on Build GRCh38	Loss	STK17A
esv2665229	Chr.7:43585279 - 43592478 on Build GRCh38	Deletion	STK17A
esv3612996	Chr.7:43537785 - 43656356 on Build GRCh38	Gain	COA1 STK17A HECW1
esv22147	Chr.7:43585305 - 43592406 on Build GRCh38	Loss	STK17A
dgv11292n54	Chr.7:43583207 - 43592243 on Build GRCh38	Loss	STK17A
dgv11296n54	Chr.7:43588145 - 43592243 on Build GRCh38	Loss	STK17A
nsv518728	Chr.7:43555801 - 43614160 on Build GRCh38	Loss	COA1 STK17A HECW1
dgv1904e212	Chr.7:43588031 - 43596574 on Build GRCh38	Loss	STK17A
esv3541556	Chr.7:43584902 - 43592901 on Build GRCh38	Deletion	STK17A
dgv11293n54	Chr.7:43583370 - 43604236 on Build GRCh38	Loss	STK17A

More Information

Additional Information:

For this assay, SNP(s) [rs115540789] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
apoptotic process
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of fibroblast apoptotic process
regulation of reactive oxygen species metabolic process

Function(s)

protein serine/threonine kinase activity
ATP binding