Hs04963983_cn

• Gene Symbol: AKR1B10
• Assay Reference Genome Location: Chr.7:134529262 on build GRCh38
• Cytoband: 7q33

Target Gene Details

• Entrez Gene ID: 57016
• Gene Name: aldo-keto reductase family 1 member B10
• Gene Aliases: AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI
• Location: Chr.7:134527592-134541414 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AKR1B10	NM_020299.4			NP_064695.3
	XM_011516416.1			XP_011514718.1
	XM_011516417.2			XP_011514719.1
	AF052577.1			AAC36465.1
	AF524864.1			AAO13380.1
	BC008837.2			AAH08837.1
	BT006794.1			AAP35440.1
	CR541801.1			CAG46600.1
	U37100.1			AAC17469.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2669756	Chr.7:134525343 - 134560371 on Build GRCh38	Deletion	AKR1B15 AKR1B10
nsv1026859	Chr.7:134512710 - 134558688 on Build GRCh38	Loss	AKR1B15 AKR1B10
nsv1031083	Chr.7:134516469 - 134620674 on Build GRCh38	Loss	AKR1B15 AKR1B10

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

retinoid metabolic process
cellular aldehyde metabolic process
digestion
steroid metabolic process
farnesol catabolic process
daunorubicin metabolic process
doxorubicin metabolic process
oxidation-reduction process

Function(s)

retinal dehydrogenase activity
aldo-keto reductase (NADP) activity
protein binding
geranylgeranyl reductase activity
indanol dehydrogenase activity