Hs05020582_cn

• Gene Symbol: GRM8
• Assay Reference Genome Location: Chr.7:126463711 on build GRCh38
• Cytoband: 7q31.33

Target Gene Details

• Entrez Gene ID: 2918
• Gene Name: glutamate metabotropic receptor 8
• Gene Aliases: GLUR8, GPRC1H, MGLUR8, mGlu8
• Location: Chr.7:126438598-127253294 on Build GRCh38
• Assay Gene Location: Within Intron 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRM8	NM_000845.2			NP_000836.2
	NM_001127323.1			NP_001120795.1
	NR_028041.1
	XM_006715938.3			XP_006716001.1
	XM_011516091.1			XP_011514393.1
	XM_011516092.2			XP_011514394.1
	XM_011516094.1			XP_011514396.1
	XM_011516095.2			XP_011514397.1
	XM_011516101.2			XP_011514403.1
	XM_011516102.2			XP_011514404.1
	XM_011516103.2			XP_011514405.1
	XM_011516108.2			XP_011514410.1
	XM_017012074.1			XP_016867563.1
	XM_017012075.1			XP_016867564.1
	XM_017012076.1			XP_016867565.1
	XM_017012077.1			XP_016867566.1
	XM_017012078.1			XP_016867567.1
	XM_017012079.1			XP_016867568.1
	XM_017012080.1			XP_016867569.1
	AJ236921.1			CAB36968.1
	AJ236922.1			CAB36969.1
	AK290197.1
	AK315203.1
	AY608335.1			AAT37959.1
	BC093725.1			AAH93725.1
	BC101675.1			AAI01676.1
	EU432125.1
	U92459.1			AAB51764.1
	U95025.1			AAB72040.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3614931	Chr.7:126334896 - 126534697 on Build GRCh38	Loss	GRM8
esv3891200	Chr.7:124990785 - 126688176 on Build GRCh38	Loss	LOC101928283 LOC101928254 POT1-AS1 GRM8

More Information

Additional Information:

For this assay, SNP(s) [rs114647359] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
visual perception
sensory perception of smell
negative regulation of cAMP biosynthetic process
regulation of synaptic transmission, glutamatergic

Function(s)

group III metabotropic glutamate receptor activity
G-protein coupled receptor activity
glutamate receptor activity