Hs05110946_cn

• Gene Symbol: ADARB2
• Assay Reference Genome Location: Chr.10:1187137 on build GRCh38
• Cytoband: 10p15.3

Target Gene Details

• Entrez Gene ID: 105
• Gene Name: adenosine deaminase, RNA specific B2 (inactive)
• Gene Aliases: ADAR3, RED2
• Location: Chr.10:1177313-1737476 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADARB2	NM_018702.3			NP_061172.1
	AF034837.1			AAF78094.1
	AK055107.1
	AK057763.1
	AK289895.1
	AK307451.1
	AK308579.1
	BC137477.1
	BC139725.1
	BC140852.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv527883	Chr.10:1172090 - 1272353 on Build GRCh38	Gain	ADARB2
esv2660097	Chr.10:526001 - 1246069 on Build GRCh38	Deletion	WDR37 LARP4B LOC101930421 LOC105376341 LOC105376339 LOC101927762 IDI2 PRR26 IDI2-AS1 LINC00200 GTPBP4 DIP2C ADARB2 MIR5699 IDI1
esv2761563	Chr.10:1184503 - 1299763 on Build GRCh38	Loss	ADARB2
nsv549768	Chr.10:1120460 - 1308893 on Build GRCh38	Gain	WDR37 LINC00200 ADARB2
nsv509340	Chr.10:1186931 - 1257850 on Build GRCh38	Insertion	ADARB2
nsv1161922	Chr.10:1104778 - 1240765 on Build GRCh38	Duplication	WDR37 LINC00200 ADARB2
dgv655n100	Chr.10:1133579 - 1495256 on Build GRCh38	Gain	LOC642422 LINC00200 ADARB2
nsv1046041	Chr.10:1149274 - 2146961 on Build GRCh38	Gain	LOC642422 LINC00200 ADARB2-AS1 ADARB2 LINC00700 MIR6072
nsv1041498	Chr.10:1071260 - 1717996 on Build GRCh38	Gain	WDR37 LOC642422 LINC00200 ADARB2-AS1 ADARB2

More Information

Additional Information:

For this assay, SNP(s) [rs74400961] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mRNA processing

Function(s)

double-stranded RNA binding
single-stranded RNA binding
adenosine deaminase activity
poly(A) RNA binding
metal ion binding