Hs05135599_cn

• Gene Symbol: GRK5
• Assay Reference Genome Location: Chr.10:119210013 on build GRCh38
• Cytoband: 10q26.11

Target Gene Details

• Entrez Gene ID: 2869
• Gene Name: G protein-coupled receptor kinase 5
• Gene Aliases: GPRK5
• Location: Chr.10:119207685-119455619 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRK5	NM_005308.2			NP_005299.1
	XM_005269707.1			XP_005269764.1
	XM_005269708.1			XP_005269765.1
	AK298261.1
	AK309761.1
	AK313012.1
	BC064506.1			AAH64506.1
	L15388.1			AAA58620.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv825584	Chr.10:119167789 - 119229264 on Build GRCh38	Gain	PRDX3 GRK5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

desensitization of G-protein coupled receptor protein signaling pathway
apoptotic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
Wnt signaling pathway
response to drug
negative regulation of apoptotic process
fat cell differentiation
protein autophosphorylation
regulation of cell cycle

Function(s)

protein serine/threonine kinase activity
G-protein coupled receptor kinase activity
protein kinase C binding
protein binding
ATP binding
phospholipid binding
beta-adrenergic receptor kinase activity