Hs05165612_cn

• Gene Symbol: NEURL1
• Assay Reference Genome Location: Chr.10:103511947 on build GRCh38
• Cytoband: 10q24.33

Target Gene Details

• Entrez Gene ID: 9148
• Gene Name: neuralized E3 ubiquitin protein ligase 1
• Gene Aliases: NEUR1, NEURL, RNF67, bA416N2.1, neu, neu-1
• Location: Chr.10:103493890-103592552 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NEURL1	NM_004210.4			NP_004201.3
	XM_011540331.2			XP_011538633.1
	XM_011540335.2			XP_011538637.1
	AF029729.1			AAD01887.1
	BC026336.1			AAH26336.1
	U87864.1			AAC17474.1

Target Gene Details

• Entrez Gene ID: 102724341
• Gene Name: NEURL1 antisense RNA 1
• Gene Aliases: -
• Location: Chr.10:103479603-103517442 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NEURL1-AS1	NR_120675.1
	NR_120676.1	3	328
	AA399019.1
	BX089018.1
	BX095052.1	3	302

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv524966	Chr.10:103441820 - 103717405 on Build GRCh38	Loss	SH3PXD2A CALHM2 NEURL1-AS1 CALHM3 PDCD11 CALHM1 NEURL1
dgv966n100	Chr.10:103385173 - 103553473 on Build GRCh38	Gain	CALHM2 USMG5 NEURL1-AS1 CALHM3 PDCD11 CALHM1 NEURL1 TAF5 MIR1307
esv3577694	Chr.10:103391276 - 103553473 on Build GRCh38	Gain	CALHM2 USMG5 NEURL1-AS1 CALHM3 PDCD11 CALHM1 NEURL1 MIR1307

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

regulation of translation
protein monoubiquitination
Notch signaling pathway
sperm axoneme assembly
nervous system development
brain development
skeletal muscle tissue development
lactation
negative regulation of cell proliferation
sperm motility
positive regulation of apoptotic process
positive regulation of epidermal growth factor-activated receptor activity
negative regulation of Notch signaling pathway
positive regulation of long-term neuronal synaptic plasticity
positive regulation of filopodium assembly
positive regulation of dendritic spine development
cellular response to amino acid stimulus
positive regulation of synapse maturation

Function(s)

ubiquitin-protein transferase activity
zinc ion binding
ligase activity
translation factor activity, non-nucleic acid binding
ubiquitin protein ligase activity