Hs05278575_cn

• Gene Symbol: IKZF4
• Assay Reference Genome Location: Chr.12:56017412 on build GRCh38
• Cytoband: 12q13.2

Target Gene Details

• Entrez Gene ID: 64375
• Gene Name: IKAROS family zinc finger 4
• Gene Aliases: EOS, ZNFN1A4
• Location: Chr.12:56007647-56038435 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IKZF4	XM_005269086.3			XP_005269143.1
	XM_005269089.2			XP_005269146.1
	XM_005269090.3			XP_005269147.1
	XM_011538664.1			XP_011536966.1
	XM_011538666.2			XP_011536968.1
	XM_011538669.2			XP_011536971.1
	XM_017019805.1			XP_016875294.1
	XM_017019806.1			XP_016875295.1
	XM_017019807.1			XP_016875296.1
	XM_017019808.1			XP_016875297.1
	XM_017019809.1			XP_016875298.1
	XM_017019810.1			XP_016875299.1
	XM_017019811.1			XP_016875300.1
	XM_017019812.1			XP_016875301.1
	XM_017019813.1			XP_016875302.1
	XM_017019814.1			XP_016875303.1
	XM_017019815.1			XP_016875304.1
	XM_017019816.1			XP_016875305.1

Target Gene Details

• Entrez Gene ID: 105369781
• Gene Name: uncharacterized LOC105369781
• Gene Aliases: -
• Location: Chr.12:56010092-56025091 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105369781	NR_135023.1
	HY183314.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832424	Chr.12:55881442 - 56073133 on Build GRCh38	Loss	CDK2 LOC105369781 RAB5B DGKA PYM1 PMEL RPS26 SUOX IKZF4
nsv1051961	Chr.12:55868436 - 56235643 on Build GRCh38	Gain	ESYT1 CDK2 LOC105369781 RAB5B DGKA SLC39A5 PMEL MYL6 RNF41 RPL41 PA2G4 ZC3H10 MYL6B NABP2 PYM1 LOC107987175 ERBB3 RPS26 SUOX SMARCC2 IKZF4
nsv832427	Chr.12:55998761 - 56118990 on Build GRCh38	Loss	LOC105369781 ERBB3 RPL41 RPS26 SUOX PA2G4 ZC3H10 IKZF4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter

Function(s)

transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
protein heterodimerization activity