Hs05353902_cn

• Gene Symbol: PIGB
• Assay Reference Genome Location: Chr.15:55322690 on build GRCh38
• Cytoband: 15q21.3

Target Gene Details

• Entrez Gene ID: 9488
• Gene Name: phosphatidylinositol glycan anchor biosynthesis class B
• Gene Aliases: GPI-MT-III, PIG-B
• Location: Chr.15:55318935-55355648 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIGB	NM_004855.4			NP_004846.4
	XM_005254795.4			XP_005254852.1
	XM_011522235.2			XP_011520537.1
	XM_011522236.2			XP_011520538.1
	XM_011522237.2			XP_011520539.1
	XM_017022730.1			XP_016878219.1
	XM_017022731.1			XP_016878220.1
	XM_017022732.1			XP_016878221.1
	AK223330.1			BAD97050.1
	AK293666.1
	AK314706.1
	BC017711.1			AAH17711.1
	D42138.1			BAA07709.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2761899	Chr.15:53592144 - 55643724 on Build GRCh38	Gain+Loss	C15orf65 RAB27A LOC107984745 DYX1C1 PIGB RSL24D1 LOC105370829 CCPG1 PRTG DYX1C1-CCPG1 WDR72 UNC13C MIR628 PYGO1 PIGBOS1
nsv569523	Chr.15:55263404 - 55544506 on Build GRCh38	Gain	C15orf65 RAB27A LOC107984745 DYX1C1-CCPG1 DYX1C1 PIGB MIR628 CCPG1 PYGO1 PIGBOS1
nsv1043789	Chr.15:55108674 - 55800256 on Build GRCh38	Gain	C15orf65 PRTG RAB27A LOC107984745 DYX1C1-CCPG1 DYX1C1 PIGB RSL24D1 MIR628 CCPG1 PYGO1 PIGBOS1
esv3569598	Chr.15:55270429 - 55410270 on Build GRCh38	Gain	C15orf65 RAB27A DYX1C1-CCPG1 PIGB MIR628 CCPG1 PIGBOS1
nsv1036924	Chr.15:55235676 - 55324282 on Build GRCh38	Loss	RAB27A PIGB PIGBOS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

glycosyltransferase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

GPI anchor biosynthetic process
preassembly of GPI anchor in ER membrane
mannosylation

Function(s)

mannosyltransferase activity
glycolipid mannosyltransferase activity