Hs05375202_cn

• Gene Symbol: LINGO1
• Assay Reference Genome Location: Chr.15:77619025 on build GRCh38
• Cytoband: 15q24.3

Target Gene Details

• Entrez Gene ID: 84894
• Gene Name: leucine rich repeat and Ig domain containing 1
• Gene Aliases: LERN1, LRRN6A, UNQ201
• Location: Chr.15:77613024-77820900 on Build GRCh38
• Assay Gene Location: Within Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LINGO1	NM_001301186.1			NP_001288115.1
	NM_001301187.1			NP_001288116.1
	NM_001301189.1			NP_001288118.1
	NM_001301191.1			NP_001288120.1
	NM_001301192.1			NP_001288121.1
	NM_001301194.1			NP_001288123.1
	NM_001301195.1			NP_001288124.1
	NM_001301197.1			NP_001288126.1
	NM_001301198.1			NP_001288127.1
	NM_001301199.1			NP_001288128.1
	NM_001301200.1			NP_001288129.1
	NM_032808.6			NP_116197.4
	XM_011522118.2			XP_011520420.1
	XM_017022682.1			XP_016878171.1
	AK291363.1
	AY324320.1			AAQ97216.1
	AY358284.1			AAQ88651.1
	BC011057.1			AAH11057.2
	BC068558.1			AAH68558.1
	BI523562.1
	BI825536.1
	BX355455.2
	DA150164.1
	DA182630.1
	DA183673.1
	DA232085.1
	DA328735.1
	DA410114.1
	DA483616.1
	DA525603.1
	DA787289.1
	DB165168.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833060	Chr.15:77524312 - 77742862 on Build GRCh38	Gain	LOC101929457 LINGO1-AS2 LINGO1-AS1 LINGO1
esv2569789	Chr.15:77617833 - 77619407 on Build GRCh38	Deletion	LINGO1
nsv1036749	Chr.15:77591684 - 77620066 on Build GRCh38	Gain	LINGO1
esv4114	Chr.15:77618470 - 77619033 on Build GRCh38	Loss	LINGO1
nsv512407	Chr.15:77618181 - 77620049 on Build GRCh38	Loss	LINGO1
esv2749898	Chr.15:75764003 - 77933523 on Build GRCh38	Deletion	LINC00597 ISL2 PEAK1 LOC101929439 UBE2Q2 TSPAN3 TYRO3P LOC441728 LOC101929457 LINGO1-AS1 FBXO22-AS1 HMG20A FBXO22 LINGO1 SCAPER MIR3713 TMEM266 ETFA LINGO1-AS2 NRG4 LOC645752 PSTPIP1 RCN2
nsv1040852	Chr.15:76867896 - 77845199 on Build GRCh38	Gain	LINC00597 PEAK1 TSPAN3 LOC101929457 LINGO1-AS2 PSTPIP1 LINGO1-AS1 RCN2 HMG20A LINGO1 SCAPER
esv9490	Chr.15:77618276 - 77619126 on Build GRCh38	Loss	LINGO1
esv2102930	Chr.15:77618336 - 77619096 on Build GRCh38	Deletion	LINGO1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

signal transduction
axonogenesis
negative regulation of axonogenesis

Function(s)

epidermal growth factor receptor binding
protein binding