Hs05382302_cn

• Gene Symbol: IGF1R
• Assay Reference Genome Location: Chr.15:98652215 on build GRCh38
• Cytoband: 15q26.3

Target Gene Details

• Entrez Gene ID: 3480
• Gene Name: insulin like growth factor 1 receptor
• Gene Aliases: CD221, IGFIR, IGFR, JTK13
• Location: Chr.15:98648539-98964530 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IGF1R	NM_000875.4			NP_000866.1
	NM_001291858.1			NP_001278787.1
	XM_017022139.1			XP_016877628.1
	AB425196.1
	BC113610.1
	BC113612.1
	BC143721.1
	DR007209.1
	EU826611.1
	EU826612.1
	X04434.1			CAA28030.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv570701	Chr.15:98647822 - 98652883 on Build GRCh38	Gain	IRAIN IGF1R

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

immune response
signal transduction
positive regulation of cell proliferation
insulin receptor signaling pathway
phosphatidylinositol 3-kinase signaling
positive regulation of cell migration
peptidyl-tyrosine autophosphorylation
negative regulation of apoptotic process
positive regulation of DNA replication
regulation of JNK cascade
protein autophosphorylation
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
protein tetramerization
inactivation of MAPKK activity

Function(s)

protein tyrosine kinase activity
insulin-like growth factor-activated receptor activity
insulin receptor binding
protein binding
insulin-like growth factor binding
ATP binding
insulin-like growth factor I binding
identical protein binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding