Hs05396849_cn

• Gene Symbol: CDH15
• Assay Reference Genome Location: Chr.16:89176585 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1013
• Gene Name: cadherin 15
• Gene Aliases: CDH14, CDH3, CDHM, MCAD, MRD3
• Location: Chr.16:89171755-89195492 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH15	NM_004933.2			NP_004924.1
	AK308596.1
	AK308631.1
	BC008951.2			AAH08951.1
	D83542.1			BAA12012.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952072	Chr.16:89032193 - 89201992 on Build GRCh38	Deletion	CDH15 LOC400558 LINC00304 ACSF3 SLC22A31
nsv509638	Chr.16:89152681 - 89296203 on Build GRCh38	Insertion	CDH15 LOC400558 ZNF778 LINC00304 LOC105371414 ANKRD11 ACSF3 SLC22A31
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC400558 MIR4722 LOC100289580 LOC107987238 CDT1 LOC101927793 LOC339059 APRT LOC105371409 CTU2 ACSF3 PIEZO1 CBFA2T3 SLC22A31 GALNS PABPN1L CDH15 TRAPPC2L ZNF778 LINC00304 LOC100129697
nsv573727	Chr.16:89169527 - 89193067 on Build GRCh38	Loss	CDH15
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC400558 LOC107987238 CDT1 LOC101927793 APRT LOC105371409 ACSF3 CBFA2T3 SLC22A31 GALNS PABPN1L CDH15 TRAPPC2L LINC00304 LOC100129697
nsv573720	Chr.16:88968841 - 89184474 on Build GRCh38	Gain	CDH15 LOC400558 LINC00304 ACSF3 CBFA2T3
nsv457621	Chr.16:89100686 - 89217401 on Build GRCh38	Loss	CDH15 LOC400558 ZNF778 LINC00304 ACSF3 SLC22A31
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC400558 LOC100289580 LOC107987238 LOC100287036 CDT1 LOC101927793 LOC339059 LOC105371414 APRT LOC105371409 ANKRD11 ACSF3 PIEZO1 CBFA2T3 SLC22A31 GALNS PABPN1L CDH15 TRAPPC2L ZNF778 LINC00304 LOC100129697
dgv3066n100	Chr.16:89067685 - 89301626 on Build GRCh38	Gain	CDH15 LOC400558 ZNF778 LINC00304 LOC105371414 ANKRD11 ACSF3 SLC22A31
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	FANCA TUBB3 CYBA LOC339059 GAS8 TUBB8P7 SNAI3 ZNF276 SPIRE2 LOC105371419 SPATA2L AFG3L1P DBNDD1 LOC100129697 SNAI3-AS1 LOC107987238 VPS9D1-AS1 LOC100287036 SPATA33 DPEP1 CPNE7 GALNS MVD ZNF778 FAM157C SNORD68 CHMP1A LOC400558 LOC101927793 LOC105371409 CTU2 PABPN1L URAHP LOC107984817 PRDM7 RNF166 IL17C DEF8 MIR4722 SPG7 LOC100289580 CDT1 LOC105371414 APRT TCF25 ANKRD11 ACSF3 PIEZO1 CBFA2T3 SLC22A31 CDH15 RPL13 VPS9D1 TRAPPC2L CENPBD1 LOC101927817 MC1R LINC00304 CDK10 GAS8-AS1
dgv5320n54	Chr.16:89114475 - 89197443 on Build GRCh38	Loss	CDH15 LOC400558 LINC00304 ACSF3 SLC22A31

More Information

Additional Information:

For this assay, SNP(s) [rs72819356] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
adherens junction organization
positive regulation of muscle cell differentiation

Function(s)

calcium ion binding
protein binding