Hs05414386_cn

• Gene Symbol: NAE1
• Assay Reference Genome Location: Chr.16:66819278 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8883
• Gene Name: NEDD8 activating enzyme E1 subunit 1
• Gene Aliases: A-116A10.1, APPBP1, HPP1, ula-1
• Location: Chr.16:66802878-66830977 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NAE1	NM_001018159.1			NP_001018169.1
	NM_001018160.1			NP_001018170.1
	NM_001286500.1			NP_001273429.1
	NM_003905.3			NP_003896.1
	XM_005256215.1			XP_005256272.1
	XM_011523422.2			XP_011521724.1
	AK097680.1
	AK298159.1
	AK307677.1
	AK312784.1
	AL136798.1			CAB66732.1
	AY197612.1			AAP35030.1
	BC000480.2			AAH00480.1
	BC013301.2			AAH13301.1
	BM045535.1
	U50939.1			AAC50477.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv510690	Chr.16:66817285 - 66858281 on Build GRCh38	Deletion	NAE1 CA7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

signal transduction
mitotic DNA replication checkpoint
regulation of apoptotic process
regulation of neuron apoptotic process
protein neddylation
neuron apoptotic process

Function(s)

protein binding
NEDD8 activating enzyme activity
ubiquitin protein ligase binding
protein heterodimerization activity