Hs05462134_cn

• Gene Symbol: CDH13
• Assay Reference Genome Location: Chr.16:82648583 on build GRCh38
• Cytoband: 16q23.3

Target Gene Details

• Entrez Gene ID: 1012
• Gene Name: cadherin 13
• Gene Aliases: CDHH, P105
• Location: Chr.16:82626794-83796610 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH13	NM_001220488.1			NP_001207417.1
	NM_001220489.1			NP_001207418.1
	NM_001220490.1			NP_001207419.1
	NM_001220491.1			NP_001207420.1
	NM_001220492.1			NP_001207421.1
	NM_001257.4			NP_001248.1
	XM_017022848.1			XP_016878337.1
	XM_017022849.1			XP_016878338.1
	AK294277.1
	AK295886.1
	AK298612.1
	AK304592.1
	AK304733.1
	AK307862.1
	AU123178.1
	BC028624.2			AAH28624.1
	BC030653.2			AAH30653.1
	BI756586.1
	CV024366.1
	DC376661.1
	EU190357.1
	EU190358.1
	L34058.1			AAA35624.1
	U59288.1			AAB18911.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv573371	Chr.16:82131578 - 83629456 on Build GRCh38	Loss	MIR8058 LOC101928417 MIR3182 MPHOSPH6 LOC101928446 CDH13
nsv573367	Chr.16:82106956 - 83007241 on Build GRCh38	Gain	MIR8058 LOC101928417 MPHOSPH6 LOC101928446 CDH13
nsv833305	Chr.16:82530283 - 82688479 on Build GRCh38	Gain	CDH13
nsv1061288	Chr.16:82146152 - 83636829 on Build GRCh38	Gain+Loss	MIR8058 LOC101928417 MIR3182 MPHOSPH6 LOC101928446 CDH13
dgv3051n100	Chr.16:82138730 - 83654472 on Build GRCh38	Gain	MIR8058 LOC101928417 MIR3182 MPHOSPH6 LOC101928446 CDH13
esv275004	Chr.16:82645927 - 82648882 on Build GRCh38	Loss	CDH13
nsv1065896	Chr.16:82179912 - 82698389 on Build GRCh38	Gain	MIR8058 CDH13
dgv5253n54	Chr.16:82148499 - 83630977 on Build GRCh38	Gain	MIR8058 LOC101928417 MIR3182 MPHOSPH6 LOC101928446 CDH13
nsv1059718	Chr.16:82530449 - 82776398 on Build GRCh38	Loss	MIR8058 LOC101928446 CDH13

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

mitotic cell cycle
positive regulation of endothelial cell proliferation
positive regulation of cell-matrix adhesion
sprouting angiogenesis
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
Rho protein signal transduction
negative regulation of cell proliferation
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Rac protein signal transduction
lamellipodium assembly
regulation of endocytosis
positive regulation of cell migration
adherens junction organization
regulation of epidermal growth factor receptor signaling pathway
endothelial cell migration
keratinocyte proliferation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of calcium-mediated signaling
positive regulation of positive chemotaxis
localization within membrane
low-density lipoprotein particle mediated signaling

Function(s)

calcium ion binding
low-density lipoprotein particle binding
protein homodimerization activity
cadherin binding
adiponectin binding
lipoprotein particle binding