Hs05463557_cn

• Gene Symbol: NQO1
• Assay Reference Genome Location: Chr.16:69723963 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 1728
• Gene Name: NAD(P)H quinone dehydrogenase 1
• Gene Aliases: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
• Location: Chr.16:69709401-69726668 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NQO1	NM_000903.2			NP_000894.1
	NM_001025433.1			NP_001020604.1
	NM_001025434.1			NP_001020605.1
	NM_001286137.1			NP_001273066.1
	AK223050.1			BAD96770.1
	AK297125.1
	AK297979.1
	AK298896.1
	AK307533.1
	AK309513.1
	AK312368.1
	AK316246.1
	BC007659.2			AAH07659.1
	BC107739.1			AAI07740.1
	BE903613.1
	CD014005.1
	DC331440.1
	J03934.1			AAA59940.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517207	Chr.16:69711242 - 69738011 on Build GRCh38	Loss	NQO1
esv3892878	Chr.16:69687512 - 69844258 on Build GRCh38	Gain	NQO1 WWP2 NFAT5 NOB1
esv3638928	Chr.16:69677077 - 69756070 on Build GRCh38	Gain	NQO1 NFAT5 NOB1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of cellular amino acid metabolic process
xenobiotic metabolic process
nitric oxide biosynthetic process
synaptic transmission, cholinergic
aging
response to nutrient
response to toxic substance
removal of superoxide radicals
response to estradiol
negative regulation of catalytic activity
positive regulation of neuron apoptotic process
response to ethanol
oxidation-reduction process

Function(s)

NAD(P)H dehydrogenase (quinone) activity
cytochrome-b5 reductase activity, acting on NAD(P)H
superoxide dismutase activity
protein binding
identical protein binding
poly(A) RNA binding