Hs05492297_cn

• Gene Symbol: KDM6B
• Assay Reference Genome Location: Chr.17:7836722 on build GRCh38
• Cytoband: 17p13.1

Target Gene Details

• Entrez Gene ID: 23135
• Gene Name: lysine demethylase 6B
• Gene Aliases: JMJD3
• Location: Chr.17:7834210-7854800 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KDM6B	XM_005256549.3			XP_005256606.1
	XM_005256551.3			XP_005256608.1
	XM_006721483.3			XP_006721546.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833351	Chr.17:7755691 - 7893863 on Build GRCh38	Loss	CYB5D1 DNAH2 KDM6B TMEM88 CHD3 NAA38

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

inflammatory response to antigenic stimulus
response to activity
hippocampus development
cell fate commitment
endothelial cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mesodermal cell differentiation
cardiac muscle cell differentiation
oxidation-reduction process
response to fungicide
cellular response to hydrogen peroxide
histone H3-K27 demethylation

Function(s)

chromatin binding
protein binding
beta-catenin binding
histone demethylase activity
sequence-specific DNA binding
metal ion binding
dioxygenase activity
histone demethylase activity (H3-K27 specific)