Hs05552897_cn

• Gene Symbol: MX1
• Assay Reference Genome Location: Chr.21:41420780 on build GRCh38
• Cytoband: 21q22.3

Target Gene Details

• Entrez Gene ID: 4599
• Gene Name: MX dynamin like GTPase 1
• Gene Aliases: IFI-78K, IFI78, MX, MxA
• Location: Chr.21:41420329-41459214 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MX1	NM_001144925.2			NP_001138397.1
	XM_011529568.2			XP_011527870.1
	XM_017028349.1			XP_016883838.1
	AK096355.1
	DA726666.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834102	Chr.21:41286267 - 41494006 on Build GRCh38	Loss	MX2 FAM3B MX1 TMPRSS2
esv1009381	Chr.21:41420102 - 41431317 on Build GRCh38	Deletion	MX1
nsv1057981	Chr.21:41290295 - 41422831 on Build GRCh38	Loss	MX2 FAM3B MX1
esv3893413	Chr.21:41410704 - 41454624 on Build GRCh38	Gain	MX1

More Information

Additional Information:

For this assay, SNP(s) [rs76428198] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

apoptotic process
defense response
signal transduction
response to virus
response to type I interferon
negative regulation of viral genome replication
innate immune response
defense response to virus
type I interferon signaling pathway

Function(s)

GTPase activity
protein binding
GTP binding