Hs05561175_cn

• Gene Symbol: APOBEC3C
• Assay Reference Genome Location: Chr.22:39016751 on build GRCh38
• Cytoband: 22q13.1

Target Gene Details

• Entrez Gene ID: 27350
• Gene Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3C
• Gene Aliases: A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3
• Location: Chr.22:39014260-39018838 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOBEC3C	NM_014508.2			NP_055323.2
	AB208979.1			BAD92216.1
	AF165520.1			AAF86650.1
	AK313272.1
	BC011739.2			AAH11739.1
	CR456394.1			CAG30280.1
	KC329528.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv962793	Chr.22:39014160 - 39017969 on Build GRCh38	Duplication	APOBEC3C
esv2763703	Chr.22:38955461 - 39034450 on Build GRCh38	Loss	APOBEC3A APOBEC3C APOBEC3D APOBEC3F APOBEC3B APOBEC3B-AS1
esv2724241	Chr.22:39014940 - 39028280 on Build GRCh38	Deletion	APOBEC3C APOBEC3D APOBEC3F
esv3647753	Chr.22:39004677 - 39029340 on Build GRCh38	Gain	APOBEC3C APOBEC3D APOBEC3F
esv3647751	Chr.22:38997523 - 39050430 on Build GRCh38	Gain	APOBEC3C APOBEC3D APOBEC3F APOBEC3B-AS1
nsv834196	Chr.22:38996564 - 39214999 on Build GRCh38	Loss	APOBEC3C APOBEC3D CBX7 APOBEC3F APOBEC3G APOBEC3H APOBEC3B-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs146055408] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

cytidine deamination
negative regulation of transposition
negative regulation of viral genome replication
innate immune response
defense response to virus
DNA demethylation

Function(s)

protein binding
zinc ion binding
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
poly(A) RNA binding