Hs05669552_cn

• Gene Symbol: PDK3
• Assay Reference Genome Location: Chr.X:24482597 on build GRCh38
• Cytoband: Xp22.11

Target Gene Details

• Entrez Gene ID: 5165
• Gene Name: pyruvate dehydrogenase kinase 3
• Gene Aliases: CMTX6, GS1-358P8.4
• Location: Chr.X:24465227-24550466 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDK3	NM_001142386.2			NP_001135858.1
	NM_005391.4			NP_005382.1
	AK301965.1
	BC015948.1			AAH15948.1
	BG717206.1
	BI549903.1
	L42452.1			AAC42011.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv2239e212	Chr.X:24474349 - 24494380 on Build GRCh38	Loss	PDK3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

glucose metabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of glucose metabolic process
peptidyl-serine phosphorylation
peroxisome proliferator activated receptor signaling pathway
cellular response to glucose stimulus
cellular response to fatty acid
hypoxia-inducible factor-1alpha signaling pathway
regulation of reactive oxygen species metabolic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
protein binding
ATP binding