Hs05726498_cn

• Gene Symbol: CASP9
• Assay Reference Genome Location: Chr.1:15491860 on build GRCh38
• Cytoband: 1p36.21

Target Gene Details

• Entrez Gene ID: 842
• Gene Name: caspase 9
• Gene Aliases: APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
• Location: Chr.1:15491401-15524912 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP9	NM_001229.4	9	2579	NP_001220.2
	NM_001278054.1	5	2129	NP_001264983.1
	NM_032996.3	9	2410	NP_127463.2
	NR_102732.1	9	2637
	NR_102733.1	9	2439
	AB209147.1	8	3435	BAD92384.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833536	Chr.1:15323505 - 15528830 on Build GRCh38	Loss	CELA2B CELA2A LOC101927441 DNAJC16 CASP9 FHAD1 CTRC EFHD2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
cellular response to DNA damage stimulus
aging
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
platelet formation
response to cobalt ion
response to estradiol
response to lipopolysaccharide
glial cell apoptotic process
cellular response to UV
signal transduction in response to DNA damage
positive regulation of neuron apoptotic process
response to antibiotic
cellular response to dexamethasone stimulus
extrinsic apoptotic signaling pathway in absence of ligand
regulation of response to DNA damage stimulus

Function(s)

cysteine-type endopeptidase activity
protein binding
enzyme activator activity
peptidase activity
SH3 domain binding
protein kinase binding
cysteine-type endopeptidase activity involved in apoptotic process