Hs05730140_cn

• Gene Symbol: S100A7A
• Assay Reference Genome Location: Chr.1:153417054 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 338324
• Gene Name: S100 calcium binding protein A7A
• Gene Aliases: NICE-2, S100A15, S100A7L1, S100A7f
• Location: Chr.1:153416524-153423225 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
S100A7A	NM_176823.3			NP_789793.1
	AY189118.1			AAO40033.1

Target Gene Details

• Entrez Gene ID: 6279
• Gene Name: S100 calcium binding protein A8
• Gene Aliases: 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8
• Location: Chr.1:153390032-153422583 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
S100A8	NM_001319198.1			NP_001306127.1
	AA401538.1
	AI126134.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv946398	Chr.1:153405218 - 153417874 on Build GRCh38	Duplication	S100A7A S100A8
nsv1002705	Chr.1:153335376 - 153553113 on Build GRCh38	Gain	S100A9 LOC101928034 S100A7L2 PGLYRP4 S100A7 S100A7A S100A8 S100A6 S100A3 S100A5 S100A4 S100A12
nsv952211	Chr.1:153415425 - 153419724 on Build GRCh38	Deletion	S100A7A S100A8

More Information

Additional Information:

For this assay, SNP(s) [rs75940104] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

calmodulin-related

Gene Ontology Categories:

Process(es)

cytokine production
leukocyte migration involved in inflammatory response
acute inflammatory response
chronic inflammatory response
positive regulation of peptide secretion
autophagy
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
response to zinc ion
astrocyte development
peptidyl-cysteine S-nitrosylation
positive regulation of cell growth
neutrophil chemotaxis
sequestering of zinc ion
response to lipopolysaccharide
chemokine production
wound healing
defense response to bacterium
innate immune response
response to ethanol
positive regulation of inflammatory response
defense response to fungus
positive regulation of NF-kappaB transcription factor activity
regulation of cytoskeleton organization
neutrophil aggregation
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

calcium ion binding
protein self-association
protein binding
microtubule binding
zinc ion binding
Toll-like receptor 4 binding
arachidonic acid binding
RAGE receptor binding