Hs05736662_cn

• Gene Symbol: PTPRF
• Assay Reference Genome Location: Chr.1:43560519 on build GRCh38
• Cytoband: 1p34.2

Target Gene Details

• Entrez Gene ID: 5792
• Gene Name: protein tyrosine phosphatase, receptor type F
• Gene Aliases: BNAH2, LAR
• Location: Chr.1:43522238-43623672 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPRF	XM_005271079.3			XP_005271136.1
	XM_005271080.3			XP_005271137.1
	XM_005271081.3			XP_005271138.1
	XM_005271082.3			XP_005271139.1
	XM_006710795.3			XP_006710858.1
	XM_006710796.3			XP_006710859.1
	XM_006710797.3			XP_006710860.1
	XM_006710798.3			XP_006710861.1
	XM_006710799.3			XP_006710862.1
	XM_006710800.3			XP_006710863.1
	XM_006710801.3			XP_006710864.1
	XM_011541871.2			XP_011540173.1
	XM_011541872.2			XP_011540174.1
	XM_011541873.2			XP_011540175.1
	XM_017001942.1			XP_016857431.1
	XM_017001943.1			XP_016857432.1
	XM_017001944.1			XP_016857433.1
	XM_017001945.1			XP_016857434.1
	XM_017001946.1			XP_016857435.1
	XM_017001947.1			XP_016857436.1
	XM_017001948.1			XP_016857437.1
	XM_017001949.1			XP_016857438.1
	XM_017001950.1			XP_016857439.1
	AB177856.1			BAD66834.1
	AB177857.1
	BC048768.1			AAH48768.1
	DQ234351.1			ABB29980.1
	Y00815.1			CAA68754.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv157n100	Chr.1:43525952 - 43606749 on Build GRCh38	Gain	PTPRF
dgv158n100	Chr.1:43559459 - 43620498 on Build GRCh38	Gain	PTPRF
dgv82e59	Chr.1:43558994 - 43561092 on Build GRCh38	Duplication	PTPRF
nsv519570	Chr.1:43539609 - 43606395 on Build GRCh38	Loss	PTPRF

More Information

Additional Information:

For this assay, SNP(s) [rs68191270] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

cell adhesion
transmembrane receptor protein tyrosine phosphatase signaling pathway
chemical synaptic transmission
cell migration
neuron projection regeneration
peptidyl-tyrosine dephosphorylation
regulation of axon regeneration
negative regulation of receptor binding

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
heparin binding
protein complex binding
chondroitin sulfate proteoglycan binding