Hs05793098_cn

• Gene Symbol: AGO1
• Assay Reference Genome Location: Chr.1:35872126 on build GRCh38
• Cytoband: 1p34.3

Target Gene Details

• Entrez Gene ID: 26523
• Gene Name: argonaute 1, RISC catalytic component
• Gene Aliases: EIF2C, EIF2C1, GERP95, Q99, hAgo1
• Location: Chr.1:35869808-35929610 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGO1	NM_001317123.1			NP_001304052.1
	AK001622.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834680	Chr.1:35660621 - 35892216 on Build GRCh38	Gain	C1orf216 AGO4 AGO1 CLSPN

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process
transcription, DNA-templated
Wnt signaling pathway, calcium modulating pathway
RNA secondary structure unwinding
miRNA metabolic process
gene silencing by RNA
pre-miRNA processing
posttranscriptional gene silencing by RNA
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol-mediated signaling
mRNA cleavage involved in gene silencing by siRNA

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core binding
core promoter binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
endoribonuclease activity
protein binding
miRNA binding
poly(A) RNA binding