Hs05800186_cn

• Gene Symbol: TPR
• Assay Reference Genome Location: Chr.1:186318052 on build GRCh38
• Cytoband: 1q31.1

Target Gene Details

• Entrez Gene ID: 7175
• Gene Name: translocated promoter region, nuclear basket protein
• Gene Aliases: -
• Location: Chr.1:186311652-186375325 on Build GRCh38
• Assay Gene Location: Within Intron 48

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPR	NM_003292.2			NP_003283.2
	U69668.1			AAB48030.1
	X66397.1			CAA47021.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3575361	Chr.1:186266048 - 186604612 on Build GRCh38	Gain	C1orf27 LOC102724919 PDC PRG4 TPR OCLM
esv3890826	Chr.1:185730915 - 186448352 on Build GRCh38	Gain	C1orf27 LOC102724919 PDC PRG4 HMCN1 TPR OCLM

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK import into nucleus
RNA import into nucleus
RNA export from nucleus
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
protein export from nucleus
nuclear pore organization
mitotic nuclear division
mitotic nuclear envelope disassembly
mitotic spindle assembly checkpoint
biological_process
regulation of mRNA export from nucleus
regulation of glucose transport
regulation of mitotic sister chromatid separation
viral process
protein sumoylation
viral transcription
gene silencing by RNA
positive regulation of heterochromatin assembly
regulation of protein stability
mRNA export from nucleus in response to heat stress
cellular response to heat
cellular response to interferon-alpha
regulation of protein import into nucleus
positive regulation of protein import into nucleus
nuclear matrix organization
negative regulation of translational initiation
regulation of protein export from nucleus
positive regulation of protein export from nucleus
negative regulation of RNA export from nucleus
nuclear pore complex assembly
cell division
response to epidermal growth factor
intracellular transport of virus
positive regulation of mitotic cell cycle spindle assembly checkpoint
positive regulation of intracellular protein transport
regulation of cellular response to heat
regulation of mitotic spindle assembly

Function(s)

molecular_function
chromatin binding
mRNA binding
transporter activity
nucleocytoplasmic transporter activity
protein binding
tubulin binding
heat shock protein binding
protein homodimerization activity
protein anchor
poly(A) RNA binding
mitogen-activated protein kinase binding
dynein complex binding