Hs05812671_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130755688 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	1	38	NP_001098663.1
	NM_152698.2			NP_689911.2
	XM_011510793.2			XP_011509095.1
	AK095696.1			BAC04612.1
	AK289525.1
	AK291424.1
	BC113445.1
	BC113447.1
	BC143806.1
	DA102742.1
	DA500900.1	1	39
	DA773233.1

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	POTEE GPR148 FAM168B ARHGEF4 POTEJ AMER3 TISP43 CYP4F30P POTEI CFC1 PLEKHB2 LOC440910
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	POTEE GPR148 FAM168B ARHGEF4 AMER3 CYP4F30P POTEI PLEKHB2 LOC440910
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	GPR148 FAM168B ARHGEF4 AMER3 POTEI PLEKHB2
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	POTEE GPR148 WTH3DI CYP4F30P POTEI NOC2LP2 MZT2A PLEKHB2 TUBA3D LINC01120 LOC150776 FAM168B ARHGEF4 POTEJ AMER3 MIR4784 POTEKP LOC440910 CCDC74A
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	GPR148 ARHGEF4 AMER3 POTEI
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	POTEE GPR148 FAM168B ARHGEF4 AMER3 CYP4F30P POTEI PLEKHB2 LOC440910
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	GPR148 FAM168B ARHGEF4 AMER3 POTEI PLEKHB2
dgv4075n100	Chr.2:130720375 - 131521740 on Build GRCh38	Gain	POTEE GPR148 WTH3DI POTEI NOC2LP2 MZT2A PLEKHB2 TUBA3D LINC01120 LOC150776 FAM168B ARHGEF4 AMER3 MIR4784 LOC440910
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	POTEE GPR148 WTH3DI POTEI NOC2LP2 MZT2A PLEKHB2 TUBA3D LINC01120 LOC150776 FAM168B ARHGEF4 AMER3 MIR4784 LOC440910 CCDC74A
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	POTEE GPR148 WTH3DI CYP4F30P POTEI NOC2LP2 MZT2A PLEKHB2 TUBA3D LINC01120 LOC150776 FAM168B ARHGEF4 POTEJ AMER3 MIR4784 LOC440910
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	WTH3DI TISP43 CCDC115 POTEF LINC01120 PTPN18 CFC1B POTEJ AMER3 CYP4F62P POTEKP LOC440910 ZNF806 MZT2A PLEKHB2 NOC2LP1 FAM168B SMPD4 MIR4784 MZT2B LOC101927924 TUBA3E MIR663B FAR2P2 LOC646743 POTEI FAR2P1 CFC1 TUBA3D RAB6C LOC150776 CCDC74B LOC389033 CCDC74A POTEE GPR148 C2orf27B FAM201B CYP4F30P NOC2LP2 IMP4 GPR39 ANKRD30BL LOC100507460 ARHGEF4 MED15P9 RAB6C-AS1 LINC01087 LOC107985778 C2orf27A
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	TUBA3E FAR2P2 LOC646743 TISP43 POTEI FAR2P1 CCDC115 CFC1 RAB6C POTEF PTPN18 CFC1B POTEJ AMER3 CYP4F62P CCDC74B LOC389033 GPR148 CYP4F30P IMP4 NOC2LP1 ARHGEF4 MED15P9 RAB6C-AS1 SMPD4 MZT2B LOC107985778 LOC101927924

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding