Hs05812671_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130755688 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	1	38	NP_001098663.1
	NM_152698.2			NP_689911.2
	XM_011510793.2			XP_011509095.1
	AK095696.1			BAC04612.1
	AK289525.1
	AK291424.1
	BC113445.1
	BC113447.1
	BC143806.1
	DA102742.1
	DA500900.1	1	39
	DA773233.1

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	TISP43 FAM168B AMER3 CYP4F30P ARHGEF4 POTEI GPR148 POTEE POTEJ LOC440910 PLEKHB2 CFC1
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	FAM168B AMER3 CYP4F30P ARHGEF4 POTEI GPR148 POTEE LOC440910 PLEKHB2
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	AMER3 CYP4F30P MZT2A TUBA3D CCDC74A POTEKP WTH3DI PLEKHB2 FAM168B MIR4784 NOC2LP2 LOC150776 ARHGEF4 POTEI LINC01120 GPR148 POTEE POTEJ LOC440910
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	FAM168B AMER3 ARHGEF4 POTEI GPR148 PLEKHB2
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	FAM168B AMER3 CYP4F30P ARHGEF4 POTEI GPR148 POTEE LOC440910 PLEKHB2
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	AMER3 ARHGEF4 POTEI GPR148
nsv1014723	Chr.2:130720375 - 131379551 on Build GRCh38	Loss	FAM168B AMER3 ARHGEF4 POTEI GPR148 POTEE LOC440910 WTH3DI PLEKHB2
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	FAM168B AMER3 ARHGEF4 POTEI GPR148 PLEKHB2
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	AMER3 MZT2A TUBA3D CCDC74A WTH3DI PLEKHB2 FAM168B MIR4784 NOC2LP2 LOC150776 ARHGEF4 POTEI LINC01120 GPR148 POTEE LOC440910
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	AMER3 CYP4F30P MZT2A TUBA3D WTH3DI PLEKHB2 FAM168B MIR4784 NOC2LP2 LOC150776 ARHGEF4 POTEI LINC01120 GPR148 POTEE POTEJ LOC440910
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	LOC646743 GPR39 AMER3 LOC107985778 LOC100507460 MZT2B LINC01087 LOC389033 CFC1 CCDC115 NOC2LP2 IMP4 RAB6C-AS1 LOC440910 POTEF NOC2LP1 MIR663B C2orf27A CCDC74A FAR2P1 MIR4784 TUBA3E LOC150776 C2orf27B TISP43 FAM201B MZT2A MED15P9 PLEKHB2 PTPN18 ZNF806 LOC101927924 ARHGEF4 LINC01120 CCDC74B POTEJ ANKRD30BL CYP4F30P FAR2P2 TUBA3D CYP4F62P CFC1B POTEKP WTH3DI FAM168B SMPD4 RAB6C POTEI GPR148 POTEE
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	TISP43 LOC646743 AMER3 LOC107985778 MZT2B LOC389033 MED15P9 CFC1 CCDC115 PTPN18 LOC101927924 ARHGEF4 CCDC74B IMP4 POTEJ RAB6C-AS1 POTEF CYP4F30P FAR2P2 NOC2LP1 CYP4F62P CFC1B FAR2P1 SMPD4 RAB6C TUBA3E POTEI GPR148

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding