Hs05890691_cn

• Gene Symbol: ATG7
• Assay Reference Genome Location: Chr.3:11273070 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 10533
• Gene Name: autophagy related 7
• Gene Aliases: APG7-LIKE, APG7L, GSA7
• Location: Chr.3:11272324-11564704 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ATG7	NM_001136031.2			NP_001129503.2
	NM_001144912.1			NP_001138384.1
	NM_006395.2			NP_006386.1
	XM_006712931.3			XP_006712994.1
	XM_006712932.3			XP_006712995.1
	XM_006712933.3			XP_006712996.1
	XM_011533277.2			XP_011531579.1
	XM_011533278.2			XP_011531580.1
	XM_011533279.2			XP_011531581.1
	XM_011533280.2			XP_011531582.1
	XM_011533281.2			XP_011531583.1
	XM_011533282.2			XP_011531584.1
	XM_011533283.2			XP_011531585.1
	XM_011533284.2			XP_011531586.1
	XM_011533285.2			XP_011531587.1
	XM_011533286.2			XP_011531588.1
	XM_017005543.1			XP_016861032.1
	XM_017005544.1			XP_016861033.1
	XM_017005546.1			XP_016861035.1
	XM_017005547.1			XP_016861036.1
	XM_017005548.1			XP_016861037.1
	XM_017005549.1			XP_016861038.1
	XM_017005550.1			XP_016861039.1
	XM_017005551.1			XP_016861040.1
	XM_017005552.1			XP_016861041.1
	AK075221.1
	AK298833.1
	AK303694.1
	AK314504.1
	BC000091.2			AAH00091.1
	DA177126.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv436362	Chr.3:10048344 - 11860564 on Build GRCh38	Deletion	VGLL4 GHRLOS SLC6A1 VHL GHRL ATP2B2 SEC13 BRK1 FANCD2OS ATP2B2-IT2 MIR378B FANCD2 TAMM41 SLC6A1-AS1 TATDN2 MIR885 IRAK2 SLC6A11 LOC101927467 LINC00606 LINC00852 HRH1 ATG7
dgv762e201	Chr.3:10008967 - 11913136 on Build GRCh38	Deletion	VHL ATP2B2 SEC13 CIDECP MIR378B TAMM41 SLC6A1-AS1 TATDN2 LINC00606 LINC00852 ATG7 EMC3 VGLL4 GHRLOS SLC6A1 GHRL BRK1 FANCD2OS ATP2B2-IT2 FANCD2 LOC401052 MIR885 IRAK2 FANCD2P2 SLC6A11 LOC101927467 HRH1
nsv1121603	Chr.3:10071433 - 11889279 on Build GRCh38	Deletion	VGLL4 GHRLOS SLC6A1 VHL GHRL ATP2B2 SEC13 BRK1 FANCD2OS ATP2B2-IT2 MIR378B FANCD2 TAMM41 SLC6A1-AS1 TATDN2 MIR885 IRAK2 FANCD2P2 SLC6A11 LOC101927467 LINC00606 LINC00852 HRH1 ATG7
nsv436869	Chr.3:10064456 - 11877985 on Build GRCh38	Insertion	VGLL4 GHRLOS SLC6A1 VHL GHRL ATP2B2 SEC13 BRK1 FANCD2OS ATP2B2-IT2 MIR378B FANCD2 TAMM41 SLC6A1-AS1 TATDN2 MIR885 IRAK2 FANCD2P2 SLC6A11 LOC101927467 LINC00606 LINC00852 HRH1 ATG7
nsv1073204	Chr.3:9996548 - 11875005 on Build GRCh38	Deletion	VHL ATP2B2 SEC13 EMC3-AS1 CIDECP MIR378B TAMM41 SLC6A1-AS1 TATDN2 LINC00606 LINC00852 ATG7 EMC3 VGLL4 GHRLOS SLC6A1 GHRL BRK1 FANCD2OS ATP2B2-IT2 FANCD2 LOC401052 MIR885 IRAK2 FANCD2P2 SLC6A11 LOC101927467 HRH1

More Information

Additional Information:

For this assay, SNP(s) [rs113339927] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

cellular protein modification process
protein lipidation
C-terminal protein lipidation
cellular response to nitrogen starvation
cellular response to starvation
positive regulation of autophagy
protein transport
macroautophagy
positive regulation of macroautophagy
protein ubiquitination
positive regulation of protein modification process
piecemeal microautophagy of nucleus
suppression by virus of host autophagy
positive regulation of apoptotic process
late nucleophagy
positive regulation of protein catabolic process
defense response to virus
membrane fusion
cellular response to hyperoxia
regulation of mitophagy

Function(s)

ubiquitin activating enzyme activity
protein binding
transcription factor binding
Atg12 activating enzyme activity
Atg8 activating enzyme activity
protein homodimerization activity