Hs05943353_cn

• Gene Symbol: MTHFD2L
• Assay Reference Genome Location: Chr.4:74141779 on build GRCh38
• Cytoband: 4q13.3

Target Gene Details

• Entrez Gene ID: 441024
• Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
• Gene Aliases: -
• Location: Chr.4:74123280-74303099 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTHFD2L	XM_017008225.1			XP_016863714.1
	XM_017008226.1			XP_016863715.1
	XM_017008231.1			XP_016863720.1
	XM_017008232.1			XP_016863721.1
	BC032771.1			AAH32771.1
	BG566009.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1004768	Chr.4:73908655 - 74243862 on Build GRCh38	Gain	PF4 PPBPP2 MTHFD2L CXCL3 CXCL2 PPBP CXCL5
nsv525980	Chr.4:73865809 - 74556070 on Build GRCh38	Gain	PF4 LOC105377276 PPBPP2 MTHFD2L CXCL3 CXCL2 PPBP EREG EPGN CXCL5 CXCL1 AREG

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

histidine biosynthetic process
purine nucleotide biosynthetic process
one-carbon metabolic process
methionine biosynthetic process
10-formyltetrahydrofolate metabolic process
folic acid-containing compound biosynthetic process
tetrahydrofolate interconversion
folic acid metabolic process
oxidation-reduction process

Function(s)

formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase (NAD+) activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity