Hs05950321_cn

• Gene Symbol: FGF2
• Assay Reference Genome Location: Chr.4:122847355 on build GRCh38
• Cytoband: 4q28.1

Target Gene Details

• Entrez Gene ID: 2247
• Gene Name: fibroblast growth factor 2
• Gene Aliases: BFGF, FGF-2, FGFB, HBGF-2
• Location: Chr.4:122826708-122898235 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FGF2	NM_002006.4			NP_001997.5
	AB451321.1
	AB451450.1
	AY820133.1			AAV70487.1
	J04513.1			AAA52532.1
	M17599.1			AAA52534.1
	M27968.1			AAA52448.1
	S47380.1			AAD13853.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
branching involved in ureteric bud morphogenesis
positive regulation of endothelial cell proliferation
cell migration involved in sprouting angiogenesis
phosphatidylinositol biosynthetic process
chemotaxis
signal transduction
Ras protein signal transduction
nervous system development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
organ morphogenesis
negative regulation of fibroblast migration
positive regulation of phospholipase C activity
regulation of phosphatidylinositol 3-kinase signaling
growth factor dependent regulation of skeletal muscle satellite cell proliferation
peptidyl-tyrosine phosphorylation
extracellular matrix organization
hyaluronan catabolic process
inositol phosphate biosynthetic process
somatic stem cell population maintenance
phosphatidylinositol-3-phosphate biosynthetic process
wound healing
positive regulation of cell fate specification
positive regulation of MAP kinase activity
positive regulation of blood vessel endothelial cell migration
negative regulation of blood vessel endothelial cell migration
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
embryonic morphogenesis
positive chemotaxis
release of sequestered calcium ion into cytosol
positive regulation of cell division
positive regulation of cardiac muscle cell proliferation
negative regulation of cell death
chondroblast differentiation
negative regulation of wound healing
positive regulation of ERK1 and ERK2 cascade
positive regulation of sprouting angiogenesis
regulation of endothelial cell chemotaxis to fibroblast growth factor
positive regulation of endothelial cell chemotaxis to fibroblast growth factor

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
cytokine activity
protein binding
growth factor activity
heparin binding
1-phosphatidylinositol-3-kinase activity
ligand-dependent nuclear receptor transcription coactivator activity
chemoattractant activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity