Hs05979490_cn

• Gene Symbol: PDE8B
• Assay Reference Genome Location: Chr.5:77185739 on build GRCh38
• Cytoband: 5q13.3

Target Gene Details

• Entrez Gene ID: 8622
• Gene Name: phosphodiesterase 8B
• Gene Aliases: ADSD, PPNAD3
• Location: Chr.5:77180252-77428256 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE8B	XM_005248623.4			XP_005248680.1
	XM_005248624.4			XP_005248681.1
	XM_011543701.2			XP_011542003.1
	XM_017010007.1			XP_016865496.1
	XM_017010008.1			XP_016865497.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv469515	Chr.5:77080181 - 77230847 on Build GRCh38	Loss	SNORA47 ZBED3 ZBED3-AS1 PDE8B

More Information

Additional Information:

For this assay, SNP(s) [rs117818206] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
cyclic nucleotide metabolic process
negative regulation of insulin secretion

Function(s)

3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
metal ion binding