Hs06043659_cn

• Gene Symbol: SERINC5
• Assay Reference Genome Location: Chr.5:80119566 on build GRCh38
• Cytoband: 5q14.1

Target Gene Details

• Entrez Gene ID: 256987
• Gene Name: serine incorporator 5
• Gene Aliases: C5orf12, TPO1
• Location: Chr.5:80111227-80256082 on Build GRCh38
• Assay Gene Location: Within Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERINC5	NM_001174071.2			NP_001167542.1
	NM_178276.6			NP_840060.1
	NR_126060.1
	NR_126061.1
	AF498273.1			AAP06800.1
	BC101280.2			AAI01281.1
	BC101283.2			AAI01284.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv598744	Chr.5:80092922 - 80127524 on Build GRCh38	Gain	SERINC5
esv3605549	Chr.5:80068073 - 80166801 on Build GRCh38	Loss	THBS4 SERINC5 CTD-2201I18.1

More Information

Additional Information:

For this assay, SNP(s) [rs73125904,rs73125906] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

phosphatidylserine metabolic process
sphingolipid metabolic process
phospholipid biosynthetic process
detection of virus
L-serine transport
myelination
innate immune response
defense response to virus
positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
positive regulation of serine C-palmitoyltransferase activity

Function(s)

L-serine transmembrane transporter activity