Hs06146901_cn

• Gene Symbol: CASP8AP2
• Assay Reference Genome Location: Chr.6:89842396 on build GRCh38
• Cytoband: 6q15

Target Gene Details

• Entrez Gene ID: 9994
• Gene Name: caspase 8 associated protein 2
• Gene Aliases: CED-4, FLASH, RIP25
• Location: Chr.6:89829900-89874436 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP8AP2	NM_001137667.1			NP_001131139.1
	NM_001137668.1			NP_001131140.1
	NM_012115.3			NP_036247.1
	AF154415.1			AAF03367.1
	BC056685.1			AAH56685.1
	BC132830.1
	BP192859.1
	BP363682.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv5391	Chr.6:89837037 - 89869200 on Build GRCh38	Insertion	CASP8AP2
nsv604125	Chr.6:89751706 - 90189842 on Build GRCh38	Gain	GJA10 CASP8AP2 MDN1 BACH2
esv3890901	Chr.6:89204468 - 90033564 on Build GRCh38	Gain	GJA10 CASP8AP2 MDN1 LYRM2 UBE2J1 ANKRD6 LOC101929057 GABRR2 RRAGD BACH2 GABRR1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell cycle
signal transduction
extrinsic apoptotic signaling pathway via death domain receptors
Fas signaling pathway
cellular response to mechanical stimulus
apoptotic signaling pathway
negative regulation of nucleic acid-templated transcription

Function(s)

DNA binding
transcription corepressor activity
death receptor binding
protein binding
cysteine-type endopeptidase activator activity involved in apoptotic process
peptidase activator activity involved in apoptotic process
SUMO polymer binding