Hs06268382_cn

• Gene Symbol: MICAL2
• Assay Reference Genome Location: Chr.11:12126978 on build GRCh38
• Cytoband: 11p15.3

Target Gene Details

• Entrez Gene ID: 9645
• Gene Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
• Gene Aliases: MICAL-2, MICAL2PV1, MICAL2PV2
• Location: Chr.11:12110576-12281017 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MICAL2	NM_001282663.1			NP_001269592.1
	NM_001282668.1			NP_001269597.1
	NM_014632.3			NP_055447.1
	AB018293.1
	AK302580.1
	AK302893.1
	BC044577.1			AAH44577.1
	DA246062.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv483000	Chr.11:10678454 - 12678453 on Build GRCh38	Loss	EIF4G2 MICALCL MIR6124 ZBED5-AS1 MICAL2 TEAD1 MRVI1 DKK3 LOC105376545 LOC101928053 GALNT18 PARVA LOC105376554 MIR8070 ZBED5 USP47 MIR4299 SNORD97 CTR9 CSNK2A3
nsv832068	Chr.11:12098790 - 12284080 on Build GRCh38	Gain	MIR6124 MICAL2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

heart looping
cytoskeleton organization
heart development
positive regulation of transcription via serum response element binding
sulfur oxidation
actin filament depolymerization
oxidation-reduction process

Function(s)

actin binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
NADPH:sulfur oxidoreductase activity
FAD binding