Hs06340195_cn

• Gene Symbol: PDE1B
• Assay Reference Genome Location: Chr.12:54555391 on build GRCh38
• Cytoband: 12q13.2

Target Gene Details

• Entrez Gene ID: 5153
• Gene Name: phosphodiesterase 1B
• Gene Aliases: HEL-S-79p, PDE1B1, PDES1B
• Location: Chr.12:54549393-54579239 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE1B	NM_000924.3			NP_000915.1
	NM_001288768.1			NP_001275697.1
	NM_001288769.1			NP_001275698.1
	XM_011538456.1			XP_011536758.1
	AB209200.1			BAD92437.1
	AK296422.1
	AK302899.1
	BC032226.1			AAH32226.1
	DA254686.1
	EU668337.1
	U56976.1			AAC50769.1
	U86078.1			AAC51872.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832421	Chr.12:54522913 - 54691618 on Build GRCh38	Gain	DCD NCKAP1L PPP1R1A PDE1B GLYCAM1 LACRT

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

regulation of neurotransmitter levels
response to amphetamine
cAMP catabolic process
apoptotic process
signal transduction
locomotory behavior
visual learning
monocyte differentiation
cellular response to macrophage colony-stimulating factor stimulus
regulation of dopamine metabolic process
serotonin metabolic process
cGMP catabolic process
cellular response to granulocyte macrophage colony-stimulating factor stimulus

Function(s)

3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
protein binding
calmodulin binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity
calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity