Hs06439710_cn

• Gene Symbol: USP14
• Assay Reference Genome Location: Chr.18:172877 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 9097
• Gene Name: ubiquitin specific peptidase 14
• Gene Aliases: TGT
• Location: Chr.18:158483-213739 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
USP14	NM_001037334.1			NP_001032411.1
	NM_005151.3			NP_005142.1
	AK095516.1
	AK297605.1
	AK315438.1
	BC003556.1			AAH03556.1
	BG717018.1
	BT007183.1			AAP35847.1
	CR976282.1
	U30888.1			AAB60365.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv576227	Chr.18:52933 - 322183 on Build GRCh38	Gain	COLEC12 ROCK1P1 THOC1 USP14 MIR8078
esv3641475	Chr.18:153985 - 282924 on Build GRCh38	Gain	THOC1 USP14
esv2675103	Chr.18:168526 - 177588 on Build GRCh38	Deletion	USP14
esv3641476	Chr.18:168431 - 177684 on Build GRCh38	Loss	USP14
dgv3300n100	Chr.18:11543 - 190140 on Build GRCh38	Gain	ROCK1P1 USP14 MIR8078
nsv1064150	Chr.18:99036 - 321710 on Build GRCh38	Gain	COLEC12 ROCK1P1 THOC1 USP14 MIR8078
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	SMCHD1 COLEC12 ROCK1P1 LOC101926997 THOC1 ENOSF1 USP14 CLUL1 TYMS EMILIN2 ADCYAP1 TYMSOS CETN1 LINC00470 CBX3P2 METTL4 LOC105376854 NDC80 LOC388456 YES1 MIR8078
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	COLEC12 ROCK1P1 THOC1 ENOSF1 USP14 CLUL1 TYMS ADCYAP1 TYMSOS CETN1 LINC00470 LOC105376854 LOC388456 YES1 MIR8078
esv3641472	Chr.18:128077 - 323706 on Build GRCh38	Loss	COLEC12 THOC1 USP14
dgv3302n100	Chr.18:136228 - 249310 on Build GRCh38	Gain	THOC1 USP14
esv3573886	Chr.18:136227 - 218394 on Build GRCh38	Gain	THOC1 USP14

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease, protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
chemical synaptic transmission
negative regulation of endopeptidase activity
protein deubiquitination
regulation of chemotaxis
regulation of proteasomal protein catabolic process
negative regulation of ER-associated ubiquitin-dependent protein catabolic process

Function(s)

cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
endopeptidase inhibitor activity
protein binding
tRNA guanylyltransferase activity
proteasome binding