Hs06460676_cn

• Gene Symbol: PHLPP1
• Assay Reference Genome Location: Chr.18:62723050 on build GRCh38
• Cytoband: 18q21.33

Target Gene Details

• Entrez Gene ID: 23239
• Gene Name: PH domain and leucine rich repeat protein phosphatase 1
• Gene Aliases: PHLPP, PLEKHE1, PPM3A, SCOP
• Location: Chr.18:62715439-62980443 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PHLPP1	NM_194449.3			NP_919431.2
	XM_011525886.1			XP_011524188.1
	AB011178.2			BAA25532.2
	AK001924.1			BAA91980.1
	AL079409.1
	BC014927.2
	BC126277.1

More Information

Additional Information:

For this assay, SNP(s) [rs71352590] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of T cell anergy
protein dephosphorylation
apoptotic process
entrainment of circadian clock
regulation of apoptotic process
regulation of MAPK cascade
regulation of JNK cascade
negative regulation of protein kinase B signaling
regulation of p38MAPK cascade

Function(s)

phosphoprotein phosphatase activity
protein binding
metal ion binding