Hs06460974_cn

• Gene Symbol: METTL4
• Assay Reference Genome Location: Chr.18:2551790 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 64863
• Gene Name: methyltransferase like 4
• Gene Aliases: HsT661
• Location: Chr.18:2537525-2571503 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
METTL4	NM_001308401.1			NP_001295330.1
	NM_022840.4			NP_073751.3
	XM_005258132.3			XP_005258189.1
	XM_005258133.2			XP_005258190.1
	XM_011525730.2			XP_011524032.1
	AK022584.1
	AK026670.1			BAB15520.1
	AK290001.1
	AL834296.1			CAD38969.1
	BC111020.1			AAI11021.1
	BC136766.1
	BC136767.1
	BX647373.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1061548	Chr.18:2163157 - 2631423 on Build GRCh38	Gain	LOC101926997 NDC80 METTL4
esv3641562	Chr.18:2395070 - 2566412 on Build GRCh38	Gain	LOC101926997 METTL4
nsv1065830	Chr.18:2263727 - 2576042 on Build GRCh38	Gain	LOC101926997 NDC80 METTL4
esv3893063	Chr.18:2306414 - 2819763 on Build GRCh38	Loss	LOC101926997 CBX3P2 SMCHD1 NDC80 METTL4
nsv576310	Chr.18:2278802 - 2566394 on Build GRCh38	Gain	LOC101926997 METTL4
esv2761986	Chr.18:2532931 - 2885250 on Build GRCh38	Gain	CBX3P2 SMCHD1 EMILIN2 NDC80 METTL4
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	CLUL1 LOC105376854 LINC00470 CBX3P2 SMCHD1 USP14 COLEC12 EMILIN2 ENOSF1 METTL4 YES1 TYMS LOC101926997 CETN1 TYMSOS LOC388456 ADCYAP1 ROCK1P1 NDC80 THOC1 MIR8078
nsv576311	Chr.18:2419932 - 2611877 on Build GRCh38	Gain	LOC101926997 NDC80 METTL4
nsv576251	Chr.18:1700238 - 3043518 on Build GRCh38	Gain	LOC101926997 LPIN2 CBX3P2 SMCHD1 EMILIN2 NDC80 METTL4 LOC727896

More Information

Additional Information:

For this assay, SNP(s) [rs66873847] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA methyltransferase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

DNA methylation on adenine

Function(s)

nucleic acid binding
site-specific DNA-methyltransferase (adenine-specific) activity