Hs06576971_cn

• Gene Symbol: SMYD2
• Assay Reference Genome Location: Chr.1:214300339 on build GRCh38
• Cytoband: 1q32.3

Target Gene Details

• Entrez Gene ID: 56950
• Gene Name: SET and MYND domain containing 2
• Gene Aliases: HSKM-B, KMT3C, ZMYND14
• Location: Chr.1:214281101-214337134 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SMYD2	NM_020197.2			NP_064582.2
	AF226053.1			AAF86953.1
	AK313868.1
	BC028104.1
	BC098133.1			AAH98133.1
	BC098276.1			AAH98276.1
	BC098335.1			AAH98335.1
	BG723585.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3588786	Chr.1:214297852 - 214300549 on Build GRCh38	Loss	SMYD2
esv2668267	Chr.1:214297842 - 214300521 on Build GRCh38	Deletion	SMYD2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
heart development
negative regulation of cell proliferation
histone H3-K36 methylation
peptidyl-lysine monomethylation
peptidyl-lysine dimethylation
regulation of DNA damage response, signal transduction by p53 class mediator
regulation of signal transduction by p53 class mediator

Function(s)

RNA polymerase II core binding
p53 binding
protein binding
lysine N-methyltransferase activity
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
metal ion binding
histone methyltransferase activity (H3-K36 specific)