Hs06617296_cn

• Gene Symbol: RAD18
• Assay Reference Genome Location: Chr.3:8914162 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 56852
• Gene Name: RAD18, E3 ubiquitin protein ligase
• Gene Aliases: RNF73
• Location: Chr.3:8877196-8969249 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RAD18	NM_020165.3			NP_064550.3
	XM_017006873.1			XP_016862362.1
	AB035274.2			BAA99284.1
	AF169796.1			AAF80856.1
	AK023075.1			BAB14392.1
	AK222771.1			BAD96491.1
	AY004333.1			AAF86618.1
	BC001302.1			AAH01302.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv275011	Chr.3:8908509 - 8918634 on Build GRCh38	Gain+Loss	RAD18
nsv518352	Chr.3:8905994 - 9089915 on Build GRCh38	Loss	RAD18 SRGAP3
nsv528867	Chr.3:8913275 - 8953502 on Build GRCh38	Loss	RAD18

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

DNA repair
postreplication repair
protein monoubiquitination
cellular response to DNA damage stimulus
response to UV
DNA damage response, detection of DNA damage
protein autoubiquitination
positive regulation of chromosome segregation
negative regulation of cell death

Function(s)

Y-form DNA binding
damaged DNA binding
protein binding
zinc ion binding
ligase activity
polyubiquitin binding
ubiquitin protein ligase binding
protein complex binding
identical protein binding
single-stranded DNA-dependent ATPase activity
ubiquitin protein ligase activity