Hs06637599_cn

• Gene Symbol: RFC4
• Assay Reference Genome Location: Chr.3:186798366 on build GRCh38
• Cytoband: 3q27.3

Target Gene Details

• Entrez Gene ID: 5984
• Gene Name: replication factor C subunit 4
• Gene Aliases: A1, RFC37
• Location: Chr.3:186789892-186806695 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RFC4	NM_002916.3			NP_002907.1
	NM_181573.2			NP_853551.1
	AK297282.1
	BC017452.1			AAH17452.1
	BC024022.1			AAH24022.1
	BM837975.1
	BT006987.1			AAP35633.1
	CR536561.1			CAG38798.1
	CX788139.1
	DA359927.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001111	Chr.3:186796249 - 187014891 on Build GRCh38	Gain	ADIPOQ RFC4 LOC102724699 ST6GAL1 ADIPOQ-AS1
esv3893839	Chr.3:186785646 - 186958667 on Build GRCh38	Gain	SNORA4 MIR1248 SNORA81 ADIPOQ SNORA63 RFC4 LOC102724699 EIF4A2 ST6GAL1 ADIPOQ-AS1
esv2759206	Chr.3:186619345 - 186849537 on Build GRCh38	Loss	SNORA4 MIR1248 SNORA81 SNORA63 AHSG KNG1 ADIPOQ FETUB HRG SNORD2 RFC4 LOC102724699 EIF4A2
dgv5005n100	Chr.3:186709551 - 186836503 on Build GRCh38	Gain	SNORA4 MIR1248 SNORA81 SNORA63 SNORD2 RFC4 LOC102724699 KNG1 EIF4A2
nsv1012615	Chr.3:186676249 - 186950429 on Build GRCh38	Gain	SNORA4 MIR1248 SNORA81 SNORA63 KNG1 ST6GAL1 ADIPOQ HRG SNORD2 RFC4 LOC102724699 EIF4A2 ADIPOQ-AS1
esv34136	Chr.3:186697095 - 187036942 on Build GRCh38	Loss	SNORA4 MIR1248 SNORA81 ADIPOQ SNORA63 SNORD2 RFC4 LOC102724699 KNG1 EIF4A2 ST6GAL1 ADIPOQ-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs73886088] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed DNA polymerase

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
DNA replication
DNA strand elongation involved in DNA replication
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
positive regulation of DNA-directed DNA polymerase activity
regulation of signal transduction by p53 class mediator

Function(s)

DNA clamp loader activity
protein binding
ATP binding
enzyme binding
single-stranded DNA-dependent ATPase activity