Hs06764476_cn

• Gene Symbol: TDP2
• Assay Reference Genome Location: Chr.6:24665232 on build GRCh38
• Cytoband: 6p22.3

Target Gene Details

• Entrez Gene ID: 51567
• Gene Name: tyrosyl-DNA phosphodiesterase 2
• Gene Aliases: AD022, EAP2, EAPII, TTRAP, dJ30M3.3, hTDP2
• Location: Chr.6:24649977-24666887 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TDP2	NM_016614.2			NP_057698.2
	AF201687.1			AAG35600.1
	AF223469.1			AAF64144.1
	AJ269473.1			CAB92966.1
	AJ420495.1
	AK002168.1			BAA92119.1
	AK296623.1
	AK298699.1
	AK308836.1
	BC017553.2			AAH17553.1
	BC110375.1			AAI10376.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv601165	Chr.6:24632414 - 24665779 on Build GRCh38	Loss	KIAA0319 TDP2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

double-strand break repair
cell surface receptor signaling pathway
nucleic acid phosphodiester bond hydrolysis
negative regulation of nucleic acid-templated transcription

Function(s)

magnesium ion binding
single-stranded DNA binding
transcription corepressor activity
nuclease activity
protein binding
manganese ion binding
tyrosyl-RNA phosphodiesterase activity
5'-tyrosyl-DNA phosphodiesterase activity