Hs06815579_cn

• Gene Symbol: PDE10A
• Assay Reference Genome Location: Chr.6:165328419 on build GRCh38
• Cytoband: 6q27

Target Gene Details

• Entrez Gene ID: 10846
• Gene Name: phosphodiesterase 10A
• Gene Aliases: ADSD2, HSPDE10A, IOLOD, LINC00473, PDE10A19
• Location: Chr.6:165327287-165988121 on Build GRCh38
• Assay Gene Location: Within Exon 31

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE10A	NM_001130690.2	22	7063	NP_001124162.1
	NM_006661.3	23	7191	NP_006652.1
	XM_006715321.3	22	8388	XP_006715384.1
	XM_011535387.2	24	9183	XP_011533689.2
	XM_011535388.2	23	8516	XP_011533690.1
	XM_011535393.2	22	6991	XP_011533695.1
	XM_017010194.1	24	9187	XP_016865683.1
	XM_017010195.1	22	6936	XP_016865684.1
	XM_017010196.1	24	8634	XP_016865685.1
	AK098543.1	1	560
	KU232567.1	22	7434

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508438	Chr.6:165289866 - 165347160 on Build GRCh38	Deletion	PDE10A C6orf118
nsv5586	Chr.6:165280959 - 165333728 on Build GRCh38	Deletion	PDE10A C6orf118
nsv605245	Chr.6:165129197 - 165432415 on Build GRCh38	Gain	PDE10A C6orf118

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
regulation of protein kinase A signaling
regulation of cAMP-mediated signaling
cGMP catabolic process

Function(s)

3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
drug binding
cAMP binding
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity