Hs07048876_cn

• Gene Symbol: KLC1
• Assay Reference Genome Location: Chr.14:103633622 on build GRCh38
• Cytoband: 14q32.33

Target Gene Details

• Entrez Gene ID: 3831
• Gene Name: kinesin light chain 1
• Gene Aliases: KLC, KNS2, KNS2A
• Location: Chr.14:103629188-103701551 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLC1	NM_001130107.1			NP_001123579.1
	NM_005552.4			NP_005543.2
	NM_182923.3			NP_891553.2
	AF527736.1			AAP85635.1
	AK294508.1
	AY180164.2			AAO62549.1
	BC008881.2			AAH08881.1
	BP274336.1
	DA501532.1
	L04733.1			AAA16576.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3635603	Chr.14:103624778 - 103714856 on Build GRCh38	Gain	LOC107984648 XRCC3 KLC1
nsv832883	Chr.14:103461350 - 103654616 on Build GRCh38	Loss	CKB MARK3 BAG5 TRMT61A APOPT1 KLC1
nsv566023	Chr.14:103595309 - 103731914 on Build GRCh38	Loss	LOC107984648 ZFYVE21 XRCC3 KLC1
nsv1054574	Chr.14:103210111 - 105365114 on Build GRCh38	Loss	LOC105370687 ADSSL1 C14orf79 ASPG CDCA4 LOC105370691 MIR6765 XRCC3 PACS2 LOC107984648 ZBTB42 LOC105370708 INF2 NUDT14 RD3L SIVA1 TDRD9 TMEM179 BAG5 KIF26A APOPT1 AKT1 MIR203A SNORA28 LINC00638 C14orf180 LOC102723354 AHNAK2 LOC388022 C14orf2 ZFYVE21 PPP1R13B MIR203B LINC00637 KLC1 BRF1 MIR4710 BTBD6 EIF5 CEP170B JAG2 CKB MARK3 LOC101929634 PLD4 GPR132 LOC105378183 TRMT61A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cytoskeletal protein, microtubule binding motor protein, microtubule or microtubule-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

retrograde vesicle-mediated transport, Golgi to ER
microtubule-based movement
viral process
antigen processing and presentation of exogenous peptide antigen via MHC class II
stress granule disassembly

Function(s)

motor activity
microtubule motor activity
protein binding