Hs07072702_cn

• Gene Symbol: NDRG2
• Assay Reference Genome Location: Chr.14:21028930 on build GRCh38
• Cytoband: 14q11.2

Target Gene Details

• Entrez Gene ID: 57447
• Gene Name: NDRG family member 2
• Gene Aliases: SYLD
• Location: Chr.14:21016763-21070872 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDRG2	NM_001282211.1			NP_001269140.1
	AK293514.1

Target Gene Details

• Entrez Gene ID: 122664
• Gene Name: tubulin polymerization promoting protein family member 2
• Gene Aliases: C14orf8, CT152, P18, p25beta
• Location: Chr.14:21024262-21036352 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPPP2	XM_017020966.1			XP_016876455.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428293	Chr.14:20747949 - 21063624 on Build GRCh38	Gain+Loss	RNASE7 TPPP2 EDDM3A NDRG2 MIR6717 RNASE1 LOC101929718 RNASE13 RNASE2 RNASE3 SLC39A2 EDDM3B ARHGEF40 RNASE6 ECRP RNASE8 METTL17
nsv832740	Chr.14:20863901 - 21076893 on Build GRCh38	Gain	RNASE7 TPPP2 NDRG2 MIR6717 LOC101929718 RNASE13 RNASE2 RNASE3 SLC39A2 ARHGEF40 ECRP RNASE8 METTL17

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease, non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

negative regulation of cytokine production
signal transduction
regulation of vascular endothelial growth factor production
Wnt signaling pathway
substantia nigra development
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production

Function(s)

molecular_function
protein binding