Hs07197859_cn

• Gene Symbol: TGM2
• Assay Reference Genome Location: Chr.20:38133196 on build GRCh38
• Cytoband: 20q11.23

Target Gene Details

• Entrez Gene ID: 7052
• Gene Name: transglutaminase 2
• Gene Aliases: TG(C), TGC
• Location: Chr.20:38127387-38166578 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TGM2	NM_001323316.1			NP_001310245.1
	NM_001323317.1			NP_001310246.1
	NM_001323318.1			NP_001310247.1
	NM_004613.3			NP_004604.2
	XM_011529028.1			XP_011527330.1
	AK058031.1
	AK126508.1	1	565
	AK291714.1
	AK295775.1
	AK300292.1
	AK314618.1
	AY675221.1			AAT79353.1
	BQ938957.1
	EU794665.1
	M55153.1			AAA63261.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv585963	Chr.20:38088540 - 38228214 on Build GRCh38	Gain	RPRD1B TGM2 KIAA1755
nsv1057334	Chr.20:37793679 - 38139909 on Build GRCh38	Loss	CTNNBL1 TTI1 RPRD1B VSTM2L TGM2
esv3893333	Chr.20:38132166 - 38140631 on Build GRCh38	Loss	TGM2
dgv4308n100	Chr.20:38087420 - 38226717 on Build GRCh38	Gain	RPRD1B TGM2 KIAA1755
nsv833972	Chr.20:37949948 - 38188839 on Build GRCh38	Loss	TTI1 RPRD1B TGM2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transferase

Gene Ontology Categories:

Process(es)

phospholipase C-activating G-protein coupled receptor signaling pathway
peptide cross-linking
negative regulation of endoplasmic reticulum calcium ion concentration
positive regulation of apoptotic process
apoptotic cell clearance
positive regulation of cell adhesion
positive regulation of mitochondrial calcium ion concentration
branching involved in salivary gland morphogenesis
salivary gland cavitation

Function(s)

protein-glutamine gamma-glutamyltransferase activity
protein binding
metal ion binding