Hs07402258_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88942691 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1
	BP282804.1

Target Gene Details

• Entrez Gene ID: 100129697
• Gene Name: uncharacterized LOC100129697
• Gene Aliases: -
• Location: Chr.16:88940039-88951524 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100129697	NM_001290330.1			NP_001277259.1
	AK130238.1			BAC85311.1
	HY074528.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC107987238 APRT LOC100129697 CBFA2T3 GALNS LOC101927793 PIEZO1 TRAPPC2L LOC105371409 CDT1 PABPN1L
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC107987238 APRT CTU2 GALNS SLC22A31 TRAPPC2L CDH15 LOC400558 LINC00304 LOC339059 MIR4722 PABPN1L ACSF3 LOC100129697 CBFA2T3 LOC101927793 PIEZO1 LOC100289580 ZNF778 LOC105371409 CDT1
nsv1066077	Chr.16:88916836 - 89035141 on Build GRCh38	Gain	LOC100129697 CBFA2T3 LOC105371409
nsv573719	Chr.16:88933306 - 88957164 on Build GRCh38	Loss	LOC100129697 CBFA2T3
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC107987238 APRT GALNS SLC22A31 TRAPPC2L CDH15 LOC400558 LINC00304 PABPN1L ACSF3 LOC100129697 CBFA2T3 LOC101927793 LOC105371409 CDT1
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC107987238 APRT GALNS SLC22A31 TRAPPC2L CDH15 ANKRD11 LOC400558 LINC00304 LOC339059 PABPN1L ACSF3 LOC100129697 CBFA2T3 LOC100287036 LOC101927793 PIEZO1 LOC100289580 ZNF778 LOC105371409 CDT1 LOC105371414
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC107987238 APRT LOC100129697 CBFA2T3 GALNS LOC101927793 TRAPPC2L LOC105371409 CDT1 PABPN1L
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LOC107987238 APRT GALNS TRAPPC2L CDH15 LOC400558 LINC00304 PABPN1L ACSF3 LOC100129697 CBFA2T3 LOC101927793 LOC105371409 CDT1
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC107987238 APRT GALNS SLC22A31 LOC107984817 CDH15 CENPBD1 SPIRE2 SPG7 LINC00304 LOC339059 PABPN1L IL17C LOC100129697 LOC100287036 LOC100289580 RNF166 GAS8-AS1 SNAI3-AS1 TCF25 URAHP LOC105371414 DPEP1 CHMP1A CTU2 CPNE7 SPATA33 FAM157C TRAPPC2L GAS8 ANKRD11 LOC400558 SPATA2L DEF8 VPS9D1 PIEZO1 ZNF778 DBNDD1 CDT1 AFG3L1P ZNF276 RPL13 SNAI3 LOC105371419 MIR4722 ACSF3 LOC101927793 LOC101927817 LOC105371409 FANCA CYBA PRDM7 TUBB3 TUBB8P7 SNORD68 MVD CDK10 CBFA2T3 MC1R VPS9D1-AS1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	LOC107987238 APRT CTU2 GALNS TRAPPC2L LOC339059 MIR4722 PABPN1L LOC100129697 CBFA2T3 LOC101927793 PIEZO1 LOC100289580 LOC105371409 CDT1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding