Hs07402284_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88942899 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1
	BP282804.1

Target Gene Details

• Entrez Gene ID: 100129697
• Gene Name: uncharacterized LOC100129697
• Gene Aliases: -
• Location: Chr.16:88940039-88951524 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100129697	NM_001290330.1			NP_001277259.1
	AK130238.1			BAC85311.1
	HY074528.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC105371409 PIEZO1 TRAPPC2L LOC101927793 LOC107987238 LOC100129697 GALNS CBFA2T3 PABPN1L CDT1 APRT
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	TRAPPC2L LOC107987238 LOC100129697 GALNS LOC339059 CBFA2T3 PABPN1L CTU2 APRT SLC22A31 ACSF3 LOC105371409 PIEZO1 MIR4722 LOC100289580 LOC101927793 LOC400558 LINC00304 CDT1 CDH15 ZNF778
nsv1066077	Chr.16:88916836 - 89035141 on Build GRCh38	Gain	LOC105371409 LOC100129697 CBFA2T3
nsv573719	Chr.16:88933306 - 88957164 on Build GRCh38	Loss	LOC100129697 CBFA2T3
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	TRAPPC2L LOC107987238 LOC100129697 GALNS CBFA2T3 PABPN1L APRT SLC22A31 ACSF3 LOC105371409 LOC101927793 LOC400558 LINC00304 CDT1 CDH15
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC100287036 TRAPPC2L LOC107987238 LOC100129697 GALNS LOC339059 CBFA2T3 PABPN1L APRT SLC22A31 ACSF3 LOC105371409 PIEZO1 ANKRD11 LOC100289580 LOC101927793 LOC400558 LOC105371414 LINC00304 CDT1 CDH15 ZNF778
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC105371409 TRAPPC2L LOC101927793 LOC107987238 LOC100129697 GALNS CBFA2T3 PABPN1L CDT1 APRT
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	TRAPPC2L LOC107987238 LOC100129697 GALNS CBFA2T3 PABPN1L APRT ACSF3 LOC105371409 LOC101927793 LOC400558 LINC00304 CDT1 CDH15
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	TUBB3 SPIRE2 FAM157C CBFA2T3 APRT ZNF276 SLC22A31 SPG7 RPL13 LOC101927817 DEF8 CDH15 MVD RNF166 LOC100287036 TRAPPC2L GALNS FANCA VPS9D1 DPEP1 CPNE7 ANKRD11 LOC400558 SPATA2L CHMP1A PRDM7 TCF25 VPS9D1-AS1 LINC00304 IL17C LOC107984817 LOC107987238 SNAI3-AS1 GAS8 LOC105371419 DBNDD1 PABPN1L CTU2 SNORD68 AFG3L1P CYBA LOC105371409 MC1R PIEZO1 GAS8-AS1 URAHP MIR4722 CENPBD1 SNAI3 LOC105371414 SPATA33 CDT1 ZNF778 LOC100129697 LOC339059 ACSF3 TUBB8P7 LOC100289580 LOC101927793 CDK10
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	TRAPPC2L LOC107987238 LOC100129697 GALNS LOC339059 CBFA2T3 PABPN1L CTU2 APRT LOC105371409 PIEZO1 MIR4722 LOC100289580 LOC101927793 CDT1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding