Hs07406008_cn

• Gene Symbol: ARIH2
• Assay Reference Genome Location: Chr.3:48918821 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 10425
• Gene Name: ariadne RBR E3 ubiquitin protein ligase 2
• Gene Aliases: ARI2, TRIAD1
• Location: Chr.3:48918820-48985541 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARIH2	NM_001317333.1			NP_001304262.1
	NM_001317334.1			NP_001304263.1
	NM_006321.3			NP_006312.1
	XM_011533265.1			XP_011531567.1
	XM_011533266.1			XP_011531568.1
	XM_011533267.1			XP_011531569.1
	XM_011533268.1			XP_011531570.1
	XM_011533270.1			XP_011531572.1
	XM_011533271.1			XP_011531573.1
	XM_011533273.1			XP_011531575.1
	XM_011533275.2			XP_011531577.1
	XM_017005531.1			XP_016861020.1
	XM_017005532.1			XP_016861021.1
	XM_017005534.1			XP_016861023.1
	XM_017005536.1			XP_016861025.1
	XM_017005537.1			XP_016861026.1
	XM_017005538.1			XP_016861027.1
	XM_017005539.1			XP_016861028.1
	XM_017005540.1			XP_016861029.1
	XM_017005541.1			XP_016861030.1
	AK223550.1			BAD97270.1
	BC000422.2			AAH00422.1
	BG476221.1
	BM928477.1
	CN399800.1

Target Gene Details

• Entrez Gene ID: 646450
• Gene Name: ariadne homolog 2 opposite strand
• Gene Aliases: C3orf71
• Location: Chr.3:48917788-48919385 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARIH2OS	NM_001123040.1	1	565	NP_001116512.1
	AK097724.1	1	565	BAC05151.1
	DA461567.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893694	Chr.3:48792101 - 48921349 on Build GRCh38	Loss	ARIH2 SLC25A20 PRKAR2A-AS1 PRKAR2A ARIH2OS

More Information

Additional Information:

For this assay, SNP(s) [rs150858838] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
multicellular organism development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
developmental cell growth
protein K63-linked ubiquitination
protein K48-linked ubiquitination
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion

Function(s)

ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity