Mm00006992_cn

• Gene Symbol: App
• Assay Reference Genome Location: Chr.16:85120643 on build GRCm38
• Cytoband: 16C3.3

Target Gene Details

• Entrez Gene ID: 11820
• Gene Name: amyloid beta (A4) precursor protein
• Gene Aliases: Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
• Location: Chr.16:84954436-85173952 on Build GRCm38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
App	NM_001198823.1	2	261	NP_001185752.1
	NM_001198824.1	2	261	NP_001185753.1
	NM_001198825.1	2	261	NP_001185754.1
	NM_001198826.1	2	261	NP_001185755.1
	NM_007471.3	2	261	NP_031497.2
	AK128971.1	2	270
	AK133639.1	2	259
	AK147543.1	2	297	BAE27986.1
	AK148439.1	2	133
	AK159245.1	2	270	BAE34927.1
	AK159352.1	2	268
	AK159718.1	2	247	BAE35313.1
	AK161976.1	2	237
	AK194233.1	1	35
	AK204174.1	2	80
	AK218334.1	2	80
	AK218597.1
	AY267348.1	2	112	AAP23169.1
	BC070409.1	2	257	AAH70409.1
	M18373.1	2	250	AAA37139.1
	U84012.1	2	250	AAB41502.1
	X59379.1	2	180

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

suckling behavior
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
apoptotic process
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
nervous system development
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
negative regulation of peptidase activity
regulation of gene expression
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
collateral sprouting in absence of injury
regulation of synapse structure or activity
neuromuscular process controlling balance
synaptic growth at neuromuscular junction
protein homooligomerization
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
peptidase inhibitor activity
acetylcholine receptor binding
identical protein binding
metal ion binding
transition metal ion binding
PTB domain binding
growth factor receptor binding