Mm00007004_cn

• Gene Symbol: App
• Assay Reference Genome Location: Chr.16:84978222 on build GRCm38
• Cytoband: 16C3.3

Target Gene Details

• Entrez Gene ID: 11820
• Gene Name: amyloid beta (A4) precursor protein
• Gene Aliases: Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
• Location: Chr.16:84954436-85173952 on Build GRCm38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
App	NM_001198823.1	14	1900	NP_001185752.1
	NM_001198824.1	13	1843	NP_001185753.1
	NM_001198825.1	13	1843	NP_001185754.1
	NM_001198826.1	14	1900	NP_001185755.1
	NM_007471.3	12	1675	NP_031497.2
	AK052448.1	2	96	BAC34997.1
	AK076506.1	6	595	BAC36369.1
	AK128971.1	13	1852
	AK133639.1	13	1840
	AK147543.1	12	1711	BAE27986.1
	AK148439.1	14	1773
	AK159245.1	14	1909	BAE34927.1
	AK159718.1	14	1886	BAE35313.1
	AK161854.1	7	756
	AK161976.1	12	1650
	AK190051.1	2	94
	AK191213.1	2	106
	AK191703.1	2	94
	AK191711.1	2	94
	AK192103.1	2	94
	AK192320.1	2	94
	AK192899.1	2	94
	AK192938.1	2	94
	AK194133.1	1	94
	AK197763.1	2	98
	AK198568.1	2	94
	AK199923.1	2	94
	AK200960.1	2	95
	AK201130.1	2	94
	AK202486.1	2	94
	AK202618.1	2	94
	AK209458.1	3	262
	AK211859.1	2	173
	AK216049.1	2	94
	AK216591.1	2	94
	AK218128.1	2	173
	AY267348.1	14	1751	AAP23169.1
	BC005490.1	10	1264	AAH05490.1
	BC070409.1	12	1671	AAH70409.1
	M18373.1	12	1664	AAA37139.1
	U84012.1	12	1664	AAB41502.1
	X59379.1	12	1594

Target Gene Details

• Entrez Gene ID: 100038614
• Gene Name: predicted gene 10791
• Gene Aliases: ENSMUSG00000074933
• Location: Chr.16:84972211-84979451 on Build GRCm38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Gm10791	NR_045889.1
	AK082307.1	3	2201
	AK166404.1			BAE38756.1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

suckling behavior
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
apoptotic process
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
nervous system development
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
negative regulation of peptidase activity
regulation of gene expression
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
collateral sprouting in absence of injury
regulation of synapse structure or activity
neuromuscular process controlling balance
synaptic growth at neuromuscular junction
protein homooligomerization
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis
biological_process

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
peptidase inhibitor activity
acetylcholine receptor binding
identical protein binding
metal ion binding
transition metal ion binding
PTB domain binding
growth factor receptor binding
molecular_function